BRD1 and CEP70

Data Source:
BioGRID (two hybrid)

		BRD1	CEP70
Description		bromodomain containing 1	centrosomal protein 70
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Nuclear Speck Dendrite Histone H3-K14 Acetyltransferase Complex Perikaryon MOZ/MORF Histone Acetyltransferase Complex	Centrosome Cytosol
	Molecular Function	Protein Binding Histone Binding Histone Acetyltransferase Activity (H3-K23 Specific) Metal Ion Binding	Protein Binding Identical Protein Binding Gamma-tubulin Binding
	Biological Process	Response To Immobilization Stress Erythrocyte Maturation Histone H3 Acetylation Histone H3-K23 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Erythrocyte Differentiation Response To Electrical Stimulus	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Cytoskeleton Organization Ciliary Basal Body-plasma Membrane Docking
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Mean platelet volume ( 27863252) Metabolite levels ( 23823483) Natriuretic peptide levels ( 21273288) Pulse pressure ( 30224653) Schizophrenia ( 23894747) Urinary albumin excretion ( 32277301) Youthful appearance (self-reported) ( 32339537)	Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575) Male-pattern baldness ( 28196072)
Interacting Genes		17 interacting genes: CASP8 CEP126 CEP70 DISC1 FEZ1 FEZ2 H2AX H3C14 HMBOX1 MAGEA11 PICK1 RUBCN SS18L1 TFIP11 VIM ZNF512B ZRANB1	242 interacting genes: ABT1 AGBL2 AKAP17A ARHGEF3 ARMCX1 ATP5PO ATXN7 BARD1 BAZ2B BEX2 BRD1 BRMS1 BRMS1L BRPF1 BYSL C1orf35 C7orf25 C8orf33 CARD9 CAVIN3 CBX8 CCDC187 CCDC85B CDC37 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL CWF19L2 DAXX DAZAP2 DDX41 DDX6 DNAJB11 DNTTIP2 DVL3 EAF1 EBNA1BP2 EIF3D ELOA ELOA2 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM161B FAM214B FAM90A1 GADD45GIP1 GAS8 GATAD2B GCC1 GEM GLYCTK GPATCH2L GPATCH4 GPX7 GSE1 HAUS1 HDAC4 HDAC6 HIC2 HMGB4 HOXB5 HOXC8 HSPD1 IK INO80B INPP5J IPCEF1 IQCE IQUB ITPKB KANK2 KANSL1 KAT14 KAT5 KAT7 KDM1A KRI1 KRT31 LAMTOR5 LCOR LENG1 LENG8 LIN37 LNX1 MAB21L2 MAGOH MBD3 MCM10 MCRS1 MEST METTL17 MFAP1 MKRN3 MRPL44 NEBL NIPSNAP3A NKAP NKAPD1 NOL12 NOP2 NOP53 NOXA1 NRIP1 NTAQ1 NUSAP1 ODAD4 PAM16 PIBF1 PIMREG PKN1 PLA2G2A PPFIA1 PPIG PPP1R16B PPP1R18 PRKRIP1 PRPF18 PRPF3 PRPF31 PSMA1 PSORS1C2 RASSF10 RBM10 RCOR3 RHPN1 RNF169 RNF6 RPL13 SCNM1 SEC14L1 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SNW1 SOD2 SPANXN3 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TBC1D22B TBC1D30 TCAF1 TCEANC TEAD4 TLK2 TRAF3IP3 TRIM29 TRIM3 TRIM42 TSFM TSGA10IP TSHZ3 TTLL10 TXLNB TXN2 USP2 UTP11 UTP14A UTP14C UTP25 UTP3 VXN WT1 YJU2 ZBTB16 ZBTB24 ZBTB4 ZBTB47 ZBTB48 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZFHX3 ZFP1 ZFP91 ZGPAT ZNF136 ZNF140 ZNF148 ZNF165 ZNF169 ZNF17 ZNF20 ZNF202 ZNF227 ZNF239 ZNF264 ZNF266 ZNF302 ZNF329 ZNF35 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF433 ZNF439 ZNF490 ZNF491 ZNF555 ZNF557 ZNF572 ZNF574 ZNF578 ZNF587 ZNF599 ZNF607 ZNF648 ZNF669 ZNF688 ZNF696 ZNF775 ZNF777 ZNF785 ZNF835 ZNF860 ZSCAN12 ZSCAN21 ZSCAN23
Entrez ID		23774	80321
HPRD ID		06848	16779
Ensembl ID		ENSG00000100425	ENSG00000114107
Uniprot IDs		A0A024R4V5 A0A024R4W4 O95696 Q59G93	A0A140VJG2 B7Z2D2 Q8NHQ1
PDB IDs		2KU3 2L43 2LQ6 3LYI 3RCW 4Z02 5AME 5AMF 5FG6 5GK9 5N49 5PNX 5PNY 5PNZ 5PO0 5PO1 5PO2 5PO3 5PO4 5PO5 5PO6 5PO7 5PO8 5PO9 5POA 5POB 5POC 5POD 5POE 5POF 5POG 5POH 5POI 5POJ 5POK 5POL 5POM 5PON 5POO 5POP 5POQ 5POR 5POS 5POT 5POU 5POV 5POW 5POX 5POY 5POZ 5PP0 5PP1 5PP2 5PP3 5PP4 5PP5 5PP6 5PP7 5PP8 5PP9 5PPA 5PPB 5PPC 5PPD 5PPE 5PPF 5PPG 5PPH 5PPI 5PPJ 5PPK 5PPL 5PPM 5PPN 5PPO 5PPP 5PPQ 5PPR 5PPS 5PPT 5PPU 5PPV 5PPW 5PPX 5PPY 5PPZ 5PQ0 5PQ1 5PQ2 5PQ3 5PQ4 5PQ5 5PQ6 5PQ7 5PQ8 5PQ9 5PQA 5PQB 5PQC 5PQD 5PQE 5PQF 5PQG 5PQH 5PQI 5PQJ 5PQK 5PQL 5PQM 5PQN 5PQO 5PQP 5PQQ 5PQR 5PQS 5PQT 5PQU 5PQV 5PQW 5PQX 5PQY 5PQZ 5PR0 5PR1 5PR2 5PR4 5PR5 5PR6 5PR7 5PR8 5PR9 5PRA 5PRB 5PRD 5PRE 5PRF 5PRG 5PRH 5PRI 5PRJ 5PRK 5PRL 5PRM 5PRO 5PRP 5PRQ 5PRR 5PRS 5PRT 5PRU 5PRV 5PRW 5PRX 5PRY 5PRZ 5PS0 5PS1 5PS2 5PS3 5PS4 5PS5 5PS6 5PS7 5PS8 5PS9 5PSA 5PSB 5PSC 5PSD 5PSE 5PSF 5PSG 5PSH 5PSI 5PSJ 5PSK 5PSL 5PSM 5PSN 5PSO 5PSP 5PSQ 5PSR 5PSS 5PST 5PSU 5PSV 5PSW 5PSX 5PSY 5PSZ 5PT0 5PT1 5PT2 5PT3 5PT4 5PT5 5PT6 5PT7 5PT8 5PT9 5PTA 5PTB 5PTC 5PTE 5PTF 5PTG 5PTH 5PTJ 5PTK 5PTL 5PTM 5PTN 5PTO 5PTQ 5PTR 5PTS 5PTT 5PTU 5PTV 5PTW 5PTX 5PTY 5PTZ 5PU0 5PU1 5PU2 5PU3 5PU4 5PU5 5PU6 5PU7 5PU8 5PU9 5PUA 5PUB 5PUC 5PUD 5PUE 5PUF 5PUG 5PUH 5PUI 5PUJ 5PUK 5PUL 5PUM 5PUN 5PUO 5PUP 5PUQ 5PUR 5PUS 5PUT 5PUU 5PUV 5PUW 5PUX 5PUY 5PUZ 5PV0 5PV1 5PV2 5PV3 5PV4 5PV5 5PV6 5PV7 5PV8 5PV9 5PVA 5PVB 5PVC 5PVD 5PVE 5PVF 5PVG 5PVH 5PVI 5PVJ 5PVK 5PVL 5PVM 5PVN 5PVO 5PVP 5PVQ 5PVR 5PVS 5PVT 5PVU 5PVV 5PVW 5PVX 5PVY 5PVZ 5PW0 5PW1 5PW2 5PW3 5PW4 5PW5 5PW6 5PW7 5PW8 5PW9 5PWA 5PWB 6IN2 6MAJ 6MAK
Enriched GO Terms of Interacting Partners?
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