LRRC25 and CLDN19

Data Source:
BioGRID (two hybrid)

		LRRC25	CLDN19
Description		leucine rich repeat containing 25	claudin 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Structural Molecule Activity Identical Protein Binding
	Biological Process		Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Hyperemesis gravidarum ( 29563502) Monocyte percentage of white cells ( 32888494 27863252) Severity of nausea and vomiting of pregnancy ( 29563502) Systemic lupus erythematosus ( 33536424 28714469) White blood cell count ( 32888494)
Interacting Genes		38 interacting genes: ACD AGPAT4 ANKRD46 APOL3 ATP6V0C BMP10 BRICD5 C3orf52 CD72 CLDN19 CLEC1A CLN6 CLRN2 CNIH3 CXCL9 DEFB121 DNAJC30 EDDM3B FAM3C FATE1 FPR2 GPRC5D LHFPL5 MAL OPRM1 PKMYT1 PNLIPRP1 SEC22A SEC61G SMCO4 SPNS3 TMEM120A TMEM201 TNF TRAF3IP3 TSPAN4 VAMP5 YIPF6	63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14
Entrez ID		126364	149461
HPRD ID		09597	10834
Ensembl ID		ENSG00000175489	ENSG00000164007
Uniprot IDs		Q8N386	Q8N6F1
PDB IDs
Enriched GO Terms of Interacting Partners?
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