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CLDN19 and TNFSF14
Data Source:
BioGRID
(two hybrid)
CLDN19
TNFSF14
Description
claudin 19
TNF superfamily member 14
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Junction Complex
Perinuclear Region Of Cytoplasm
Extracellular Space
Cytoplasm
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Structural Molecule Activity
Identical Protein Binding
Signaling Receptor Binding
Cytokine Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Biological Process
Positive Regulation Of Protein Phosphorylation
Cell Adhesion
Visual Perception
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Neuronal Action Potential Propagation
Negative Regulation Of Cell Migration
Actin Cytoskeleton Reorganization
Response To Stimulus
Negative Regulation Of Wound Healing
Bicellular Tight Junction Assembly
Regulation Of Transepithelial Transport
Positive Regulation Of Cell Junction Assembly
Apoptotic Process
Immune Response
Signal Transduction
T Cell Costimulation
Tumor Necrosis Factor-mediated Signaling Pathway
T Cell Proliferation
T Cell Activation
T Cell Homeostasis
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cellular Response To Mechanical Stimulus
Positive Regulation Of NIK/NF-kappaB Signaling
Pathways
Tight junction interactions
TNFR2 non-canonical NF-kB pathway
TNFs bind their physiological receptors
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Blood protein levels in cardiovascular risk (
28369058
)
Granulocyte percentage of myeloid white cells (
27863252
)
Monocyte count (
29403010
)
Monocyte percentage of white cells (
27863252
)
Multiple sclerosis (
31604244
24076602
21833088
)
Interacting Genes
63 interacting genes:
AQP6
AQP9
BCL2L13
BIK
BSCL2
BTN2A1
CD200R1
CD53
CD74
CLEC14A
CLEC2D
CLRN1
CREB3
CXCR3
CYSRT1
ERGIC3
FAM209A
FCGR1A
FCGRT
FKBP7
FNDC9
GGT7
GJA8
GORAB
GPR161
GPX8
HSD17B13
ICAM3
IFNGR2
IL3RA
KEL
KIR2DL3
KRT31
KRT34
LAPTM5
LRRC25
LRRC4C
MFF
MS4A14
MS4A4A
MUC1
PDZK1IP1
PKD2L1
PLEKHB2
PVR
SAR1A
SCARB2
SGPL1
SLAMF6
SLC10A1
SLC35C2
SPACA1
SRPK2
STOM
STOML3
SUSD3
SYNE4
TM4SF18
TMEM106C
TMEM248
TMEM52B
TMEM80
TNFSF14
22 interacting genes:
ADAM33
ADIPOQ
APP
BMP10
CLDN11
CLDN19
CXCL9
JAGN1
LHFPL3
LTB
LTBR
MAL
OLFM4
PLLP
PTTG1IP
SEC22A
SEC23A
SYS1
TMEM11
TNFRSF14
TNFRSF6B
UPK2
Entrez ID
149461
8740
HPRD ID
10834
05157
Ensembl ID
ENSG00000164007
ENSG00000125735
Uniprot IDs
Q8N6F1
O43557
PDB IDs
4EN0
4J6G
4KG8
4KGG
4KGQ
4RSU
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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