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CLDN19 and SCARB2
Data Source:
BioGRID
(two hybrid)
CLDN19
SCARB2
Description
claudin 19
scavenger receptor class B member 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Junction Complex
Perinuclear Region Of Cytoplasm
Golgi Membrane
Cytoplasm
Lysosomal Membrane
Endoplasmic Reticulum Membrane
Plasma Membrane
Focal Adhesion
Endosome Membrane
Membrane
Integral Component Of Membrane
Clathrin-coated Vesicle Membrane
Endocytic Vesicle Membrane
Late Endosome Membrane
Lysosomal Lumen
Extracellular Exosome
Molecular Function
Structural Molecule Activity
Identical Protein Binding
Virus Receptor Activity
Phosphatidylserine Binding
Transmembrane Signaling Receptor Activity
Scavenger Receptor Activity
Protein Binding
Cholesterol Binding
Enzyme Binding
Phosphatidylcholine Binding
Cargo Receptor Activity
Protein Homodimerization Activity
Biological Process
Positive Regulation Of Protein Phosphorylation
Cell Adhesion
Visual Perception
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Neuronal Action Potential Propagation
Negative Regulation Of Cell Migration
Actin Cytoskeleton Reorganization
Response To Stimulus
Negative Regulation Of Wound Healing
Bicellular Tight Junction Assembly
Regulation Of Transepithelial Transport
Positive Regulation Of Cell Junction Assembly
Protein Targeting To Lysosome
Receptor-mediated Endocytosis
Positive Regulation Of Neuron Projection Development
Aminophospholipid Transport
Regulation Of Cellular Carbohydrate Catabolic Process
Viral Entry Into Host Cell
Membrane Organization
Regulation Of Endosome Organization
Regulation Of Glucosylceramidase Activity
Regulation Of Lysosome Organization
Pathways
Tight junction interactions
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Drugs
Diseases
Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS
BMI (adjusted for smoking behaviour) (
28443625
)
Body mass index (
25673413
)
Body mass index (joint analysis main effects and smoking interaction) (
28443625
)
Estimated glomerular filtration rate (
31015462
)
Hippocampal volume (
29274321
)
Parkinson's disease (
25064009
21738487
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Interacting Genes
63 interacting genes:
AQP6
AQP9
BCL2L13
BIK
BSCL2
BTN2A1
CD200R1
CD53
CD74
CLEC14A
CLEC2D
CLRN1
CREB3
CXCR3
CYSRT1
ERGIC3
FAM209A
FCGR1A
FCGRT
FKBP7
FNDC9
GGT7
GJA8
GORAB
GPR161
GPX8
HSD17B13
ICAM3
IFNGR2
IL3RA
KEL
KIR2DL3
KRT31
KRT34
LAPTM5
LRRC25
LRRC4C
MFF
MS4A14
MS4A4A
MUC1
PDZK1IP1
PKD2L1
PLEKHB2
PVR
SAR1A
SCARB2
SGPL1
SLAMF6
SLC10A1
SLC35C2
SPACA1
SRPK2
STOM
STOML3
SUSD3
SYNE4
TM4SF18
TMEM106C
TMEM248
TMEM52B
TMEM80
TNFSF14
10 interacting genes:
AP3S1
AP3S2
CLDN19
ERGIC3
GPR37L1
GPX8
HIBADH
LAPTM4B
LMNA
THBS1
Entrez ID
149461
950
HPRD ID
10834
03772
Ensembl ID
ENSG00000164007
ENSG00000138760
Uniprot IDs
Q8N6F1
A0A024RDG6
Q14108
PDB IDs
4F7B
4Q4B
4Q4F
4TVZ
4TW0
4TW2
5UPH
5XBM
6I2K
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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