LRRC25 and APOL3

Data Source:
BioGRID (two hybrid)

		LRRC25	APOL3
Description		leucine rich repeat containing 25	apolipoprotein L3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Extracellular Region Cytoplasm Membrane
	Molecular Function	Protein Binding	Lipid Transporter Activity Lipid Binding
	Biological Process		Lipid Transport Inflammatory Response Lipoprotein Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Hyperemesis gravidarum ( 29563502) Monocyte percentage of white cells ( 32888494 27863252) Severity of nausea and vomiting of pregnancy ( 29563502) Systemic lupus erythematosus ( 33536424 28714469) White blood cell count ( 32888494)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065) Estimated glomerular filtration rate ( 31152163) Total intracranial volume ( 31530798)
Interacting Genes		38 interacting genes: ACD AGPAT4 ANKRD46 APOL3 ATP6V0C BMP10 BRICD5 C3orf52 CD72 CLDN19 CLEC1A CLN6 CLRN2 CNIH3 CXCL9 DEFB121 DNAJC30 EDDM3B FAM3C FATE1 FPR2 GPRC5D LHFPL5 MAL OPRM1 PKMYT1 PNLIPRP1 SEC22A SEC61G SMCO4 SPNS3 TMEM120A TMEM201 TNF TRAF3IP3 TSPAN4 VAMP5 YIPF6	28 interacting genes: ELOVL4 FATE1 FXYD6-FXYD2 GJA8 GJB1 GJB5 GJC1 GPR152 GPRC5D HAS3 IL7R LHFPL5 LINC00839 LRRC25 MFSD6 NCALD PMP22 RNF19B SGCB SLC16A2 SLC1A5 SLC7A14 STX1A TIMMDC1 TMEM167B TMEM237 TMEM52B TNFRSF10D
Entrez ID		126364	80833
HPRD ID		09597	06264
Ensembl ID		ENSG00000175489	ENSG00000128284
Uniprot IDs		Q8N386	A0A024R1G6 O95236
PDB IDs
Enriched GO Terms of Interacting Partners?
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