JOSD2 and COQ8A

		JOSD2	COQ8A
Description		Josephin domain containing 2	coenzyme Q8A
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GO Annotations	Cellular Component	Cytosol	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation
Pathways		Josephin domain DUBs
Drugs			Fostamatinib
Diseases			Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Interacting Genes		13 interacting genes: AHCYL1 CMTM5 COQ8A FKBP7 MDK PLA2G2A STUB1 SYP TRAPPC2 TRAPPC2B TTPA UBC YIF1A	26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM159 TMEM239 TPD52L2
Entrez ID		126119	56997
HPRD ID		15297	07375
Ensembl ID		ENSG00000161677	ENSG00000163050
Uniprot IDs		A0A024R4G2 Q7Z7N5 Q8TAC2	Q8NI60
PDB IDs		6PGV	4PED 5I35
Enriched GO Terms of Interacting Partners?
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