CKMT2 and TMED9

Data Source:
BioGRID (two hybrid)

		CKMT2	TMED9
Description		creatine kinase, mitochondrial 2	transmembrane p24 trafficking protein 9
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Synaptic Vesicle Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity	Protein Binding Syntaxin Binding
	Biological Process	Creatine Metabolic Process Muscle Contraction Phosphorylation Phosphocreatine Biosynthetic Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Positive Regulation Of Organelle Organization Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle
Pathways		Creatine metabolism	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Creatine Phosphocreatine
Diseases
GWAS			Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: ABHD6 CETN3 ELN KLHL42 LRIF1 NRF1 OLFML3 P4HA3 TMED9 UNC119	13 interacting genes: AQP9 CDC42 CKMT2 COPZ1 DDX54 ITM2A MTF2 NMT2 PLPPR2 SEC22A SEC23B THAP8 TMEM60
Entrez ID		1160	54732
HPRD ID		00425	09975
Ensembl ID		ENSG00000131730	ENSG00000184840
Uniprot IDs		A0A024RAK5 P17540	A0A024R7M0 Q9BVK6
PDB IDs		4Z9M
Enriched GO Terms of Interacting Partners?
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