MED19 and DCK

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED19	DCK
Description		mediator complex subunit 19	deoxycytidine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Mediator Complex	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Transcription Coregulator Activity Protein Binding Transcription Factor Binding	Deoxyadenosine Kinase Activity Deoxycytidine Kinase Activity Deoxyguanosine Kinase Activity ATP Binding Drug Binding Deoxynucleoside Kinase Activity Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	DAMP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process Phosphorylation Pyrimidine Nucleoside Salvage Purine-containing Compound Salvage
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Pyrimidine salvage Purine salvage
Drugs			Fludarabine 2'-Deoxycytidine Elacytarabine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Reticulocyte count ( 32888494) Schizophrenia ( 28991256 25056061 29483656)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		19 interacting genes: APP DCK DHRS7B DTX2 GRB2 HLCS KANK2 MED17 MED27 MED31 MED8 MED9 MSX1 NEDD9 NFKBIA OSTF1 RADIL RIPPLY1 ZNF76	5 interacting genes: DDX19B GOLM1 MED19 RXRG TFEC
Entrez ID		219541	1633
HPRD ID		17477	00507
Ensembl ID		ENSG00000156603	ENSG00000156136
Uniprot IDs		A0JLT2	F5CTF3 P27707
PDB IDs			1P5Z 1P60 1P61 1P62 2A2Z 2A30 2A7Q 2NO0 2NO1 2NO6 2NO7 2NO9 2NOA 2QRN 2QRO 2ZI3 2ZI4 2ZI5 2ZI6 2ZI7 2ZI9 2ZIA 3HP1 3IPX 3IPY 3KFX 3MJR 3QEJ 3QEN 3QEO 4JLJ 4JLK 4JLM 4JLN 4KCG 4L5B 4Q18 4Q19 4Q1A 4Q1B 4Q1C 4Q1D 4Q1E 4Q1F 5MQJ 5MQL 5MQT
Enriched GO Terms of Interacting Partners?
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