MED19 and OSTF1

Data Source:
BioGRID (two hybrid)

		MED19	OSTF1
Description		mediator complex subunit 19	osteoclast stimulating factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Mediator Complex	Extracellular Region Intracellular Anatomical Structure Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Transcription Coregulator Activity Protein Binding Transcription Factor Binding	Protein Binding SH3 Domain Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	Ossification Signal Transduction Neutrophil Degranulation
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Neutrophil degranulation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Reticulocyte count ( 32888494) Schizophrenia ( 28991256 25056061 29483656)	Allergic rhinitis ( 25085501) Glucose homeostasis traits ( 25524916) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Resting-state electroencephalogram vigilance ( 29703947) Systemic sclerosis ( 30247649) Urinary magnesium-to-creatinine ratio ( 29093028)
Interacting Genes		19 interacting genes: APP DCK DHRS7B DTX2 GRB2 HLCS KANK2 MED17 MED27 MED31 MED8 MED9 MSX1 NEDD9 NFKBIA OSTF1 RADIL RIPPLY1 ZNF76	51 interacting genes: AGR2 APP BORCS6 CBL CBLB CCDC33 CRX CTDSP1 CUEDC1 DPPA4 DTX3 EFS ERRFI1 FASLG FBXO7 GAPDH GGN HES7 HTT KHDRBS1 KLHL42 LATS1 LMNA MAPK6 MED19 MEOX2 NFYC NUTM1 NUTM2F PBX4 PICK1 REL RP2 SDCBP SF1 SF3A2 SMN1 SNW1 SOCS7 SYNGAP1 TRIB3 TRIM54 VPS37B WASF1 WASHC1 WASL YPEL3 ZBTB42 ZBTB7B ZNF655 ZNF688
Entrez ID		219541	26578
HPRD ID		17477	17808
Ensembl ID		ENSG00000156603	ENSG00000134996
Uniprot IDs		A0JLT2	Q92882
PDB IDs			1X2K 1ZLM 3EHQ 3EHR
Enriched GO Terms of Interacting Partners?
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