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U2AF2 and CHERP
Data Source:
BioGRID
(two hybrid, two hybrid, affinity chromatography technology)
U2AF2
CHERP
Description
U2 small nuclear RNA auxiliary factor 2
calcium homeostasis endoplasmic reticulum protein
Image
No pdb structure
GO Annotations
Cellular Component
Commitment Complex
Prp19 Complex
Nucleus
Nucleoplasm
Spliceosomal Complex
Nuclear Speck
U2-type Prespliceosome
U2AF Complex
Nucleoplasm
Cytoplasm
Membrane
Sarcoplasmic Reticulum Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
RNA Binding
Protein Binding
Poly-pyrimidine Tract Binding
Enzyme Binding
Pre-mRNA 3'-splice Site Binding
C2H2 Zinc Finger Domain Binding
RNA Binding
Protein Binding
Ion Channel Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Export From Nucleus
MRNA Export From Nucleus
MRNA 3'-end Processing
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of RNA Splicing
Negative Regulation Of MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Cellular Calcium Ion Homeostasis
Nervous System Development
Negative Regulation Of Cell Population Proliferation
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Menopause (age at onset) (
26414677
)
Interacting Genes
75 interacting genes:
APBB1
ATXN1
BEND7
CCAR1
CDC42
CHERP
CHIC2
CPSF7
DACH1
DDX39B
DDX6
DPPA2
DVL2
EPB41
FUBP1
GEMIN2
GLIS2
HLA-DMA
HMBOX1
IL7R
INO80B
KHDC4
KHDRBS3
LURAP1
MAP1B
MRPL15
NKAPD1
OTUB2
PHF5A
PIN1
POLR2A
PRPF3
PRPF40A
PUF60
QKI
RBFOX2
RBM11
RBM39
RBM4
RBMY1F
RBMY1J
SAP30BP
SCAF11
SF1
SF3B1
SF3B2
SF3B3
SF3B4
SF3B5
SF3B6
SMAD5
SNRPA
SRPK1
SRPK2
SRSF1
SRSF11
SRSF3
STAC3
SUGP1
SUMO2
TCERG1
TCF23
THAP1
TLE5
TOP1
U2AF1
U2AF1L5
WT1
ZNF107
ZNF526
ZNF57
ZNF71
ZNF835
ZRSR2
ZRSR2P1
48 interacting genes:
ADAMTSL4
AGGF1
APBB1
ARGLU1
C1orf94
CCAR1
CLK3
EWSR1
FASTK
FIGN
FRA10AC1
HNRNPH3
KRTAP11-1
LASP1
LUC7L
MAGED1
MIR106B
MIR200C
MIR363
MIRLET7A2
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7G
MIRLET7I
PPIL4
PRPF38A
PRPF40A
RACK1
RBFOX2
RBM23
RBM39
RBM7
RNPS1
SART1
SAXO1
SF3B4
SNRNP27
SNRNP70
SORBS3
SRPK1
SRPK2
TLE3
TTC14
U2AF1
U2AF2
USP54
WBP4
Entrez ID
11338
10523
HPRD ID
01872
13051
Ensembl ID
ENSG00000063244
ENSG00000085872
Uniprot IDs
P26368
Q8IWX8
PDB IDs
1JMT
1O0P
1OPI
1U2F
2G4B
2HZC
2M0G
2U2F
2YH0
2YH1
3VAF
3VAG
3VAH
3VAI
3VAJ
3VAK
3VAL
3VAM
4FXW
4TU7
4TU8
4TU9
5EV1
5EV2
5EV3
5EV4
5W0G
5W0H
6TR0
6XLV
6XLW
6XLX
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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