CHERP and FIGN

Data Source:
BioGRID (two hybrid)

		CHERP	FIGN
Description		calcium homeostasis endoplasmic reticulum protein	fidgetin, microtubule severing factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Microtubule Organizing Center Microtubule Nuclear Matrix
	Molecular Function	RNA Binding Protein Binding Ion Channel Binding	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade	Cell Cycle Cytoplasmic Microtubule Organization Microtubule Severing Cell Division
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Blood pressure ( 24954895 21572416 21909110) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Chronic kidney disease ( 26831199) Coronary artery disease ( 32469254 33020668) Diastolic blood pressure ( 28739976 27618452) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diisocyanate-induced asthma ( 25918132) Folate pathway vitamin levels ( 19744961) General risk tolerance (MTAG) ( 30643258) Hip circumference adjusted for BMI ( 28552196) Hypertension ( 30487518) Immunoglobulin A vasculitis ( 28698626) Mean arterial pressure ( 26390057 29403010 30487518) Platinum-induced myelosuppression in non-small cell lung cancer ( 25823687) Polycystic ovary syndrome (metabolic subtype) ( 32574161) PR interval ( 30046033 32439900) Pulse pressure ( 27841878 28739976 30487518) Response to antipsychotic treatment ( 19680635) Systolic blood pressure ( 26390057 28135244 27841878 29403010 28739976 27618447 27618452) Systolic blood pressure (cigarette smoking interaction) ( 29455858)
Interacting Genes		48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 U2AF2 USP54 WBP4	2 interacting genes: CHERP HGS
Entrez ID		10523	55137
HPRD ID		13051	07287
Ensembl ID		ENSG00000085872	ENSG00000182263
Uniprot IDs		Q8IWX8	Q5HY92
PDB IDs
Enriched GO Terms of Interacting Partners?
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