CHERP and SART1

Data Source:
BioGRID (two hybrid, two hybrid)

		CHERP	SART1
Description		calcium homeostasis endoplasmic reticulum protein	spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding Ion Channel Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Maturation Of 5S RRNA MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Cytotoxic T Cell Differentiation
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 U2AF2 USP54 WBP4	13 interacting genes: APP CHERP HSF2BP IGHE MFAP1 SNW1 SRPK2 SRSF4 SUMO2 UBE2I UBL5 WBP4 ZCCHC10
Entrez ID		10523	9092
HPRD ID		13051	10440
Ensembl ID		ENSG00000085872	ENSG00000175467
Uniprot IDs		Q8IWX8	O43290
PDB IDs			4PYU 5O9Z 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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