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U2AF2 and NKAPD1
Data Source:
BioGRID
(two hybrid)
U2AF2
NKAPD1
Description
U2 small nuclear RNA auxiliary factor 2
NKAP domain containing 1
Image
No pdb structure
GO Annotations
Cellular Component
Commitment Complex
Prp19 Complex
Nucleus
Nucleoplasm
Spliceosomal Complex
Nuclear Speck
U2-type Prespliceosome
U2AF Complex
Molecular Function
RNA Binding
Protein Binding
Poly-pyrimidine Tract Binding
Enzyme Binding
Pre-mRNA 3'-splice Site Binding
C2H2 Zinc Finger Domain Binding
Protein Binding
Identical Protein Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Export From Nucleus
MRNA Export From Nucleus
MRNA 3'-end Processing
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of RNA Splicing
Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Menopause (age at onset) (
26414677
)
Interacting Genes
75 interacting genes:
APBB1
ATXN1
BEND7
CCAR1
CDC42
CHERP
CHIC2
CPSF7
DACH1
DDX39B
DDX6
DPPA2
DVL2
EPB41
FUBP1
GEMIN2
GLIS2
HLA-DMA
HMBOX1
IL7R
INO80B
KHDC4
KHDRBS3
LURAP1
MAP1B
MRPL15
NKAPD1
OTUB2
PHF5A
PIN1
POLR2A
PRPF3
PRPF40A
PUF60
QKI
RBFOX2
RBM11
RBM39
RBM4
RBMY1F
RBMY1J
SAP30BP
SCAF11
SF1
SF3B1
SF3B2
SF3B3
SF3B4
SF3B5
SF3B6
SMAD5
SNRPA
SRPK1
SRPK2
SRSF1
SRSF11
SRSF3
STAC3
SUGP1
SUMO2
TCERG1
TCF23
THAP1
TLE5
TOP1
U2AF1
U2AF1L5
WT1
ZNF107
ZNF526
ZNF57
ZNF71
ZNF835
ZRSR2
ZRSR2P1
51 interacting genes:
AAMP
ACTN1
ACTN2
ACTN3
AGPAT3
AP1M1
AP2M1
ARL6IP4
BEND7
C1orf35
CCDC106
CCNL1
CDCA8
CEP70
COIL
CT45A1
ELOA2
EXOSC5
FAM133A
FRMD6
GAS8
GOLGA8K
H2BC15
HMGXB4
KRCC1
MACROH2A1
MAPK8
MCRS1
MKRN3
MYO15B
NKAPL
NXF1
PRPF3
PRPF40A
RBM39
RNF151
RNPS1
RP9
RPS25
S100B
SDCBP
SDCBP2
SNRNP25
SREK1IP1
STAC3
TAF1A
THAP1
TXLNA
U2AF2
ZNF317
ZNF41
Entrez ID
11338
55216
HPRD ID
01872
07695
Ensembl ID
ENSG00000063244
ENSG00000150776
Uniprot IDs
P26368
A0A024R3H5
Q6ZUT1
PDB IDs
1JMT
1O0P
1OPI
1U2F
2G4B
2HZC
2M0G
2U2F
2YH0
2YH1
3VAF
3VAG
3VAH
3VAI
3VAJ
3VAK
3VAL
3VAM
4FXW
4TU7
4TU8
4TU9
5EV1
5EV2
5EV3
5EV4
5W0G
5W0H
6TR0
6XLV
6XLW
6XLX
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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