SYNRG and GGA3

Data Source:
HPRD (two hybrid, in vivo)

		SYNRG	GGA3
Description		synergin gamma	golgi associated, gamma adaptin ear containing, ARF binding protein 3
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus AP-1 Adaptor Complex Clathrin Coat Of Trans-Golgi Network Vesicle	Lysosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding Small GTPase Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Intracellular Protein Transport Endocytosis	Protein Targeting To Lysosome Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Amyloid-beta Formation
Pathways			TBC/RABGAPs MET receptor recycling Amyloid fiber formation
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Ovarian cancer ( 23535730) Response to angiotensin II receptor blocker therapy ( 22566498)
Interacting Genes		8 interacting genes: AP1G1 AP1G2 APPBP2 CCDC91 GGA1 GGA2 GGA3 SCAMP1	38 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR GGA1 GGA2 IGF2R LITAF LRP10 M6PR P4HA3 PACS1 PLEKHB2 RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497
Entrez ID		11276	23163
HPRD ID		06291	10443
Ensembl ID		ENSG00000275066	ENSG00000125447
Uniprot IDs		Q9UMZ2	A8K6M0 B7Z456 Q9NZ52
PDB IDs		2MX7	1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8
Enriched GO Terms of Interacting Partners?
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