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RPLP1 and RCHY1
Data Source:
BioGRID
(two hybrid)
RPLP1
RCHY1
Description
ribosomal protein lateral stalk subunit P1
ring finger and CHY zinc finger domain containing 1
Image
GO Annotations
Cellular Component
Cytosol
Focal Adhesion
Cytosolic Large Ribosomal Subunit
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Speck
Intracellular Membrane-bounded Organelle
Molecular Function
Structural Constituent Of Ribosome
Protein Binding
Protein Kinase Activator Activity
Ribonucleoprotein Complex Binding
P53 Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cytoplasmic Translation
Translation
Translational Initiation
Translational Elongation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
Activation Of Protein Kinase Activity
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Error-free Translesion Synthesis
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Translesion Synthesis by POLH
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
28165464
24292274
23770605
)
Male-pattern baldness (
27182965
)
Non-response to citalopram or escitalopram and depression (
27622933
)
Metabolite levels (
23823483
)
Response to tocilizumab in rheumatoid arthritis (
22491018
)
Interacting Genes
35 interacting genes:
ANKRD13B
ASCC2
ATP5MF
BRD7
C11orf58
C15orf39
CDIPT
CDK2AP2
CLIC1
CSNK2A1
EEF1A1
GEMIN7
GSK3B
LRIF1
MAP1LC3B
MPC2
NSF
NUDT21
NUDT3
PDCD4
PFDN1
PPP2CB
PTN
RCHY1
RPA2
RPLP2
RPS6KA6
SAT1
SGO1
SUOX
TAB1
TPT1
TUBB2A
UBE2D3
XRCC6
75 interacting genes:
ADAMTSL4
AIG1
ANGPTL8
AOX1
AR
ARF4
ATN1
BIRC3
CAMK2A
CAMK2G
CDK9
CDKN1B
CHD8
CHEK2
COPE
COX6C
CREB5
CYBA
DAPK1
DCUN1D5
F7
FADS6
GFI1B
GORAB
HOXA1
HOXA2
HOXA3
HOXB1
HOXB2
HOXB5
HOXC11
HOXC4
HOXD10
HRG
KAT5
KLHL41
KRTAP9-2
LIMS2
MDM2
MEOX2
MSH3
MT2A
NKD2
NLK
NOTCH2NLA
PGLS
PLAGL2
PMM1
PRDX4
RAB11A
RBM38
RILP
RPLP1
RPN2
SEMA4C
SERPINA1
SERPINA5
SERTAD1
SRPRB
TAOK2
TMBIM1
TMEM14C
TMEM184A
TP53
TP63
TP73
TRIM8
UBASH3B
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
WDR74
ZNF160
Entrez ID
6176
25898
HPRD ID
01611
07607
Ensembl ID
ENSG00000137818
ENSG00000163743
Uniprot IDs
A0A024R608
P05386
Q96PM5
PDB IDs
2LBF
4BEH
4V6X
2JRJ
2K2C
2K2D
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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