Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CCDC85B and CCNK
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CCDC85B
CCNK
Description
coiled-coil domain containing 85B
cyclin K
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Adherens Junction
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Nucleoplasm
Cyclin/CDK Positive Transcription Elongation Factor Complex
Molecular Function
Protein Binding
Delta-catenin Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
Biological Process
Viral Process
Cell Differentiation
Negative Regulation Of Cell Growth
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Cell Cycle
Positive Regulation Of DNA-templated Transcription, Elongation
SnRNA Transcription By RNA Polymerase II
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Positive Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Serine 2 Residues
Pathways
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Asthma (
31959851
)
Scalp hair shape (
26926045
)
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Interacting Genes
138 interacting genes:
AGGF1
AKAP17A
AKIRIN2
APEX2
AQP1
BEX2
BEX3
BIRC5
C19orf25
C21orf91
C2CD6
C7orf50
C8orf48
CARD9
CCDC112
CCDC116
CCDC120
CCDC185
CCDC33
CCNK
CDK18
CDKN1A
CENPP
CEP70
CFAP53
CHCHD3
COPS4
CWC25
DEPP1
DEUP1
DOK5
DTNB
DUSP13
EIF3H
ENKD1
EPS8
EXOC7
EXOC8
EZH2
FAM107A
FAM124B
FAM13C
FAM214B
FAM27E3
FAM50B
FAM74A4
FASTKD5
FBF1
FCHSD2
FNDC11
FXR2
GCC1
GFI1B
GPANK1
HMG20B
HNRNPC
IKZF5
INO80B
KANSL1
KIAA0408
KRT17
KRT18
KRT20
KRT6A
LDOC1
LMO3
LNX1
LZTS2
MBIP
MCM10
MCRS1
MEAF6
MOAP1
MOB1A
MOB4
NDUFA5
NEK6
NIF3L1
NRIP1
NUP54
ODAD4
PBXIP1
PIDD1
PKN1
PLEKHF2
PLOD3
POLR2L
PRC1
PRPF3
PSMA1
PSMC1
PSMC6
PSMF1
RALYL
RBM41
RBM7
RGS8
RIBC2
RNF8
SCNM1
SETD5
SF3A3
SIX1
SLU7
SMARCD1
SPATA46
SYT17
SYTL4
TASOR2
TCEANC
TCHP
TEAD4
THAP7
TNNI1
TNNT1
TSPYL4
TTC14
TUBGCP4
USP2
UTP14A
UTP6
VPS72
ZBTB16
ZBTB5
ZC2HC1C
ZFC3H1
ZFP36
ZNF165
ZNF205
ZNF250
ZNF337
ZNF417
ZNF426
ZNF564
ZNF587
ZNF638
ZNF764
ZNF821
52 interacting genes:
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
CYSRT1
DDIT4L
DVL3
EFEMP2
FAM168B
FKBP6
HIVEP1
HMG20A
HNRNPH1
HNRNPH2
HOMEZ
HOXA1
HSFY1
HSFY2
KCNRG
KRTAP13-2
KRTAP19-6
KRTAP19-7
KRTAP4-12
KRTAP6-2
KRTAP8-1
LZTS2
MYCL
NDC80
NECAB2
OXER1
PIN1
POLR1C
POLR2A
POU6F2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RBPMS
RFX6
RHOXF2
RUNX1
STX11
TLE5
TSC22D4
USHBP1
USP54
ZNF446
Entrez ID
11007
8812
HPRD ID
16101
10352
Ensembl ID
ENSG00000175602
ENSG00000090061
Uniprot IDs
Q15834
A0A024R6K1
O75909
PDB IDs
2I53
4CXA
4NST
4UN0
5ACB
5EFQ
6B3E
6CKX
6TD3
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?