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CCDC85B and APEX2
Data Source:
HPRD
(two hybrid)
CCDC85B
APEX2
Description
coiled-coil domain containing 85B
apurinic/apyrimidinic endodeoxyribonuclease 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Adherens Junction
Fibrillar Center
Nucleus
Nucleoplasm
Mitochondrion
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Delta-catenin Binding
DNA Binding
DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity
Endonuclease Activity
Phosphodiesterase I Activity
Protein Binding
Zinc Ion Binding
Double-stranded DNA 3'-5' Exodeoxyribonuclease Activity
Biological Process
Viral Process
Cell Differentiation
Negative Regulation Of Cell Growth
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Base-excision Repair
DNA Recombination
Cell Cycle
Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Asthma (
31959851
)
Interacting Genes
138 interacting genes:
AGGF1
AKAP17A
AKIRIN2
APEX2
AQP1
BEX2
BEX3
BIRC5
C19orf25
C21orf91
C2CD6
C7orf50
C8orf48
CARD9
CCDC112
CCDC116
CCDC120
CCDC185
CCDC33
CCNK
CDK18
CDKN1A
CENPP
CEP70
CFAP53
CHCHD3
COPS4
CWC25
DEPP1
DEUP1
DOK5
DTNB
DUSP13
EIF3H
ENKD1
EPS8
EXOC7
EXOC8
EZH2
FAM107A
FAM124B
FAM13C
FAM214B
FAM27E3
FAM50B
FAM74A4
FASTKD5
FBF1
FCHSD2
FNDC11
FXR2
GCC1
GFI1B
GPANK1
HMG20B
HNRNPC
IKZF5
INO80B
KANSL1
KIAA0408
KRT17
KRT18
KRT20
KRT6A
LDOC1
LMO3
LNX1
LZTS2
MBIP
MCM10
MCRS1
MEAF6
MOAP1
MOB1A
MOB4
NDUFA5
NEK6
NIF3L1
NRIP1
NUP54
ODAD4
PBXIP1
PIDD1
PKN1
PLEKHF2
PLOD3
POLR2L
PRC1
PRPF3
PSMA1
PSMC1
PSMC6
PSMF1
RALYL
RBM41
RBM7
RGS8
RIBC2
RNF8
SCNM1
SETD5
SF3A3
SIX1
SLU7
SMARCD1
SPATA46
SYT17
SYTL4
TASOR2
TCEANC
TCHP
TEAD4
THAP7
TNNI1
TNNT1
TSPYL4
TTC14
TUBGCP4
USP2
UTP14A
UTP6
VPS72
ZBTB16
ZBTB5
ZC2HC1C
ZFC3H1
ZFP36
ZNF165
ZNF205
ZNF250
ZNF337
ZNF417
ZNF426
ZNF564
ZNF587
ZNF638
ZNF764
ZNF821
17 interacting genes:
APP
CALCOCO2
CCDC85B
DAPK1
EFEMP2
HOOK2
LRRK2
MAP3K1
MFHAS1
MKRN3
NEDD4L
NINL
PCNA
PGR
TRAF2
TRIM37
TSHZ3
Entrez ID
11007
27301
HPRD ID
16101
06442
Ensembl ID
ENSG00000175602
ENSG00000169188
Uniprot IDs
Q15834
B4DWI9
B7ZA71
E5KN95
Q9UBZ4
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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