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CCNK and KRTAP8-1
Data Source:
BioGRID
(two hybrid)
CCNK
KRTAP8-1
Description
cyclin K
keratin associated protein 8-1
Image
No pdb structure
GO Annotations
Cellular Component
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Nucleoplasm
Cyclin/CDK Positive Transcription Elongation Factor Complex
Cytosol
Intermediate Filament
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
Protein Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Cell Cycle
Positive Regulation Of DNA-templated Transcription, Elongation
SnRNA Transcription By RNA Polymerase II
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Positive Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Serine 2 Residues
Keratinization
Pathways
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Keratinization
Drugs
Diseases
GWAS
Scalp hair shape (
26926045
)
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Gut microbiota (bacterial taxa) (
27723756
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Interacting Genes
52 interacting genes:
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
CYSRT1
DDIT4L
DVL3
EFEMP2
FAM168B
FKBP6
HIVEP1
HMG20A
HNRNPH1
HNRNPH2
HOMEZ
HOXA1
HSFY1
HSFY2
KCNRG
KRTAP13-2
KRTAP19-6
KRTAP19-7
KRTAP4-12
KRTAP6-2
KRTAP8-1
LZTS2
MYCL
NDC80
NECAB2
OXER1
PIN1
POLR1C
POLR2A
POU6F2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RBPMS
RFX6
RHOXF2
RUNX1
STX11
TLE5
TSC22D4
USHBP1
USP54
ZNF446
78 interacting genes:
AANAT
AGXT
AOC1
ARID5A
ATG9A
ATXN1L
BANP
BCAS2
BHLHE40
C11orf16
C1orf94
C20orf85
CAMK2A
CCDC17
CCNK
CDA
CERCAM
CREB5
CRYAB
CYSRT1
DAB1
DAZAP2
DMRTB1
DTX2
FAAP20
FAM168A
FAM83A
FOXD2
FOXP3
GATA2
GCM2
GLIS2
HEY2
HOXC8
HYPK
KRTAP12-4
KRTAP19-5
KRTAP26-1
MFSD13A
MKRN3
MYOZ3
NKX2-5
NOXA1
P4HA3
PAX3
PITX1
PLSCR4
POGZ
POU6F2
PPP1R32
PROP1
PRR13
PRR35
PSMA3
RAMAC
RBPMS
RBPMS2
RNF38
RUSC1
SMR3A
SMUG1
SNRPC
TBX18
TEKT3
TIAL1
TLE5
TLX3
TMSB4X
TNIP1
TNPO2
TSPYL6
VENTX
VEZF1
YTHDF1
ZBTB32
ZC3H10
ZIC1
ZNF34
Entrez ID
8812
337879
HPRD ID
10352
11221
Ensembl ID
ENSG00000090061
ENSG00000183640
Uniprot IDs
A0A024R6K1
O75909
Q8IUC2
PDB IDs
2I53
4CXA
4NST
4UN0
5ACB
5EFQ
6B3E
6CKX
6TD3
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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