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CCNK and KRTAP4-12
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CCNK
KRTAP4-12
Description
cyclin K
keratin associated protein 4-12
Image
No pdb structure
GO Annotations
Cellular Component
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Nucleoplasm
Cyclin/CDK Positive Transcription Elongation Factor Complex
Keratin Filament
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
Protein Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Cell Cycle
Positive Regulation Of DNA-templated Transcription, Elongation
SnRNA Transcription By RNA Polymerase II
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Positive Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Serine 2 Residues
Pathways
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Scalp hair shape (
26926045
)
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Interacting Genes
52 interacting genes:
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
CYSRT1
DDIT4L
DVL3
EFEMP2
FAM168B
FKBP6
HIVEP1
HMG20A
HNRNPH1
HNRNPH2
HOMEZ
HOXA1
HSFY1
HSFY2
KCNRG
KRTAP13-2
KRTAP19-6
KRTAP19-7
KRTAP4-12
KRTAP6-2
KRTAP8-1
LZTS2
MYCL
NDC80
NECAB2
OXER1
PIN1
POLR1C
POLR2A
POU6F2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RBPMS
RFX6
RHOXF2
RUNX1
STX11
TLE5
TSC22D4
USHBP1
USP54
ZNF446
152 interacting genes:
ADAM12
ADAMTSL4
ALPP
AQP1
ATG12
ATN1
AXIN1
BAG4
BAHD1
BEX2
C10orf62
CATSPER1
CBX2
CCDC116
CCDC185
CCNK
CDC42EP1
CDX2
CHCHD3
CHIC2
CHRD
CLCNKA
CLDN2
CNNM3
CNTFR
COL8A1
CRCT1
CREB5
CRY1
CYSRT1
DBF4B
DLK2
EIF4E2
ELOA2
FAM107A
FAM27E3
FAM76B
FBXL18
FBXO34
FBXW5
FCHO1
FUCA2
GLRX3
GNE
GPATCH2L
GPRIN2
GRAP2
HHEX
HOXA1
HOXB9
IFI30
IGSF8
ILF3
KRT31
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP19-2
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP3-1
KRTAP3-2
KRTAP5-1
KRTAP5-6
KRTAP5-9
KRTAP6-2
KRTAP9-2
KRTAP9-3
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LELP1
LINGO1
LNX1
MAPKBP1
MEOX2
MRPL4
NOTCH2NLA
NPDC1
NUDT18
NUFIP2
OTX1
PCSK5
PDGFRB
PFKL
PHLDA1
PLSCR1
PLSCR4
PNKP
POU4F2
PRKAB2
PRKAG1
PRR13
PTPMT1
QPRT
R3HDM2
RERE
RPS28
SHFL
SLC25A10
SLC25A6
SMCP
SPATA3
SPG7
SPRY1
SPRY2
TAP1
TBC1D16
TBC1D23
TGM1
THAP10
THAP7
TOP3B
TXNDC5
ZBTB16
ZNF165
ZNF20
ZNF250
ZNF408
ZNF414
ZNF415
ZNF417
ZNF426
ZNF439
ZNF440
ZNF497
ZNF581
ZNF638
ZNF655
ZNF696
ZNF764
ZNF837
ZSCAN26
Entrez ID
8812
83755
HPRD ID
10352
13941
Ensembl ID
ENSG00000090061
ENSG00000213416
Uniprot IDs
A0A024R6K1
O75909
Q9BQ66
PDB IDs
2I53
4CXA
4NST
4UN0
5ACB
5EFQ
6B3E
6CKX
6TD3
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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