HCST and SPOP

Data Source:
HPRD (in vitro, in vivo)

		HCST	SPOP
Description		hematopoietic cell signal transducer	speckle type BTB/POZ protein
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Signaling Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Phosphorylation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Immune Response	Protein Polyubiquitination Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Hedgehog 'on' state
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Interacting Genes		6 interacting genes: KLRK1 PIK3R1 SEC22A SPOP STARD3NL VSTM1	66 interacting genes: AEN AMOTL2 AR BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I UBE2L3 VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8
Entrez ID		10870	8405
HPRD ID		04971	16004
Ensembl ID		ENSG00000126264	ENSG00000121067
Uniprot IDs		Q9UBK5	O43791
PDB IDs			2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A
Enriched GO Terms of Interacting Partners?
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