TEPSIN and SZT2

Data Source:
BioGRID (two hybrid)

		TEPSIN	SZT2
Description		TEPSIN adaptor related protein complex 4 accessory protein	SZT2 subunit of KICSTOR complex
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Nuclear Speck AP-4 Adaptor Complex Coated Vesicle Membrane Extrinsic Component Of Organelle Membrane Nuclear Membrane Trans-Golgi Network Membrane	Lysosomal Membrane Peroxisome GATOR2 Complex KICSTOR Complex GATOR1 Complex
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process		Central Nervous System Development Post-embryonic Development Corpus Callosum Morphogenesis Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Pigmentation Protein Localization To Lysosome Regulation Of Superoxide Dismutase Activity Negative Regulation Of TORC1 Signaling
Pathways			Amino acids regulate mTORC1
Drugs
Diseases
GWAS		IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		127 interacting genes: AATK ACBD7 AGRN AP1M1 AP4B1 APOL6 APP ASAP3 ASB3 BCL2L14 BCL2L15 BHLHB9 BIRC7 BPIFA1 BTBD3 C1orf109 C1QTNF4 CBX8 CCDC146 CCNC CDC23 CINP CLCNKA CLIC3 CNTF CPNE7 CSNK2A1 CTAG1A CTAG1B CYSRT1 DEF6 DUSP29 DUSP4 DZIP1L EIF1AD FAM214B FAM90A1 FARS2 FKBP6 FLACC1 FNDC3B GNG13 GOLGA2 GPANK1 GRB10 GRIPAP1 GUCD1 HAT1 HCK HPCA HSF2BP HSPB7 IL16 IQGAP1 KCTD6 KCTD9 KHNYN KLHL38 KRT31 KRT34 KRT35 KRTAP6-2 LENG1 LGALS14 LMO3 LSM3 LYG2 MAT2B MED18 MFAP1 MLX MORF4L1 MSGN1 MTUS2 NDOR1 NEK6 NGB NME7 NR2C2AP NTAQ1 NUDT14 NUDT21 OAZ3 OR6B1 PAX9 PCDHB3 PLEKHA2 PSMA6 RAB3IP RAD51D RANBP3 RNF135 SEC14L4 SLU7 SNRNP25 SORBS2 SORBS3 SZT2 TAPBPL TBC1D13 TBC1D22B TCEA2 TCL1A TFAP2D THRSP TRAPPC2 TRAPPC2B TRAPPC6A TRIM23 TRIM45 TRIM50 TRIM54 TRIM68 TSEN15 TSEN2 TSHZ3 TSSK3 UBASH3B UTP23 VPS26C WDR25 YPEL3 ZIC1 ZMYND12 ZNF343 ZNF629 ZRSR2	5 interacting genes: CRX REL TCF4 TEPSIN ZNF655
Entrez ID		146705	23334
HPRD ID		08103	11085
Ensembl ID		ENSG00000167302	ENSG00000198198
Uniprot IDs		Q96N21	Q5T011
PDB IDs		5WF9 5WFB
Enriched GO Terms of Interacting Partners?
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