POP4 and RPP25

Data Source:
HPRD (in vitro)

		POP4	RPP25
Description		POP4 homolog, ribonuclease P/MRP subunit	ribonuclease P and MRP subunit p25
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleoplasm Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite
	Molecular Function	Ribonuclease MRP Activity Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Body mass index ( 26426971) Heart rate increase in response to exercise ( 29497042) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Metabolite levels ( 23823483)	Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		6 interacting genes: POP1 POP5 RPP14 RPP25 RPP30 RPP38	22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438
Entrez ID		10775	54913
HPRD ID		09358	15276
Ensembl ID		ENSG00000105171	ENSG00000178718
Uniprot IDs		O95707	Q9BUL9
PDB IDs		6AHR 6AHU	6AHR 6AHU 6CWX
Enriched GO Terms of Interacting Partners?
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