POP4 and RPP38

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		POP4	RPP38
Description		POP4 homolog, ribonuclease P/MRP subunit	ribonuclease P/MRP subunit p38
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleoplasm Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex	Fibrillar Center Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	Ribonuclease MRP Activity Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Body mass index ( 26426971) Heart rate increase in response to exercise ( 29497042) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Metabolite levels ( 23823483)	Clozapine-induced agranulocytosis ( 25187353) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		6 interacting genes: POP1 POP5 RPP14 RPP25 RPP30 RPP38	9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40
Entrez ID		10775	10557
HPRD ID		09358	09360
Ensembl ID		ENSG00000105171	ENSG00000152464
Uniprot IDs		O95707	P78345
PDB IDs		6AHR 6AHU	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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