RPP25 and POP1

Data Source:
HPRD (in vitro)

		RPP25	POP1
Description		ribonuclease P and MRP subunit p25	POP1 homolog, ribonuclease P/MRP subunit
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite	Ribonuclease MRP Complex Extracellular Space Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal TRNA Processing TRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus
Drugs
Diseases
GWAS		Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438	8 interacting genes: POP4 POP5 PTEN PYCARD RPP25 RPP30 RPP38 RPP40
Entrez ID		54913	10940
HPRD ID		15276	03923
Ensembl ID		ENSG00000178718	ENSG00000104356
Uniprot IDs		Q9BUL9	Q96F88 Q99575
PDB IDs		6AHR 6AHU 6CWX	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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