RPP25 and POP5

Data Source:
HPRD (in vitro)

		RPP25	POP5
Description		ribonuclease P and MRP subunit p25	POP5 homolog, ribonuclease P/MRP subunit
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite	Ribonuclease MRP Complex Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RRNA Processing TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus
Drugs
Diseases
GWAS		Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)	Chronotype ( 30696823) High light scatter reticulocyte count ( 27863252) Intake of total sugars ( 31005972)
Interacting Genes		22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438	17 interacting genes: CAMK2B CCDC102B CEP44 DCDC2 INCA1 KRT34 KRT40 NDUFAB1 POP1 POP4 REL RPP14 RPP25 RPP30 TRAF1 UBC USHBP1
Entrez ID		54913	51367
HPRD ID		15276	15158
Ensembl ID		ENSG00000178718	ENSG00000167272
Uniprot IDs		Q9BUL9	Q969H6
PDB IDs		6AHR 6AHU 6CWX	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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