POP4 and RPP14

Data Source:
HPRD (in vitro)

		POP4	RPP14
Description		POP4 homolog, ribonuclease P/MRP subunit	ribonuclease P/MRP subunit p14
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleoplasm Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex	Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	Ribonuclease MRP Activity Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Body mass index ( 26426971) Heart rate increase in response to exercise ( 29497042) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Metabolite levels ( 23823483)	Height ( 28552196) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)
Interacting Genes		6 interacting genes: POP1 POP5 RPP14 RPP25 RPP30 RPP38	22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277
Entrez ID		10775	11102
HPRD ID		09358	18001
Ensembl ID		ENSG00000105171	ENSG00000163684
Uniprot IDs		O95707	O95059
PDB IDs		6AHR 6AHU	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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