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TOB2 and CEP76
Data Source:
BioGRID
(two hybrid)
TOB2
CEP76
Description
transducer of ERBB2, 2
centrosomal protein 76
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Centrosome
Centriole
Cytosol
Protein-containing Complex
Molecular Function
Transcription Corepressor Activity
Protein Binding
Vitamin D Receptor Binding
Protein Binding
Biological Process
Female Gamete Generation
Negative Regulation Of Cell Population Proliferation
Regulation Of Gene Expression
Negative Regulation Of Osteoclast Differentiation
Positive Regulation Of Ossification
Negative Regulation Of Transcription, DNA-templated
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Centriole Replication
Ciliary Basal Body-plasma Membrane Docking
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Asthma (
31361310
)
Autism spectrum disorder or schizophrenia (
28540026
)
Meat-related diet (
32066663
)
Neuroticism (
29255261
)
Refractive error (
32231278
)
Vitiligo (
22561518
)
Interacting Genes
5 interacting genes:
BHLHE40
CEP76
CNOT7
CNOT8
RPS6KA1
105 interacting genes:
AKAP7
AKT1
ANKRD36
ASH2L
BANP
C22orf39
CABP5
CACNB3
CAPN3
CAVIN3
CCDC92
CCNK
CDK18
CENPI
CIR1
COIL
CRYBA4
CSNK1G1
CUTC
CWF19L2
DCTD
DDX6
DEAF1
DMTN
DVL3
DZIP1L
EAF1
EIF1AD
EP400P1
ERCC3
FAM90A1
GDAP2
GFAP
GORASP2
HSF2
HSPB7
ILVBL
IQUB
KDM1A
KDM4D
KIAA1143
KIFBP
KLHDC4
L3MBTL2
LATS1
LNX1
MAGEA11
MBD3
MFAP1
MISP
MLH1
MYOZ1
NEK6
NFYC
NHLRC2
NME5
PAICS
PARD6B
PATZ1
PDGFRB
PDRG1
PDZD4
PDZD7
PIN1
PKP1
PLA2G6
PLCB1
POM121
RADIL
RALGPS1
RBM41
RIPPLY3
RNF128
RPL9
SALL2
SCNM1
SH2D4A
SINHCAF
SMG9
SPG21
STK26
SUOX
TBC1D27P
TCEA2
TCEANC
TCF19
TFAP2D
THRA
TOB2
TSPOAP1
TSSC4
TTC21A
TTLL10
TUFT1
TXNDC9
VEZF1
WDFY3
YY1
ZBTB24
ZBTB4
ZMAT2
ZNF185
ZNF653
ZNF76
ZNF85
Entrez ID
10766
79959
HPRD ID
09583
12694
Ensembl ID
ENSG00000183864
ENSG00000101624
Uniprot IDs
Q14106
B4DP81
Q8TAP6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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