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IGF2BP1 and MIR145
Data Source:
BioGRID
(unspecified method)
IGF2BP1
MIR145
Description
insulin like growth factor 2 mRNA binding protein 1
microRNA 145
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Lamellipodium
Filopodium
Growth Cone
Dendritic Spine
Perinuclear Region Of Cytoplasm
CRD-mediated MRNA Stability Complex
Ribonucleoprotein Complex
Extracellular Exosome
Molecular Function
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Translation Regulator Activity
MRNA 5'-UTR Binding
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Regulation Of Cytokine Production
Nervous System Development
Regulation Of Gene Expression
Regulation Of MRNA Stability Involved In Response To Stress
Negative Regulation Of Translation
Pallium Cell Proliferation In Forebrain
Regulation Of MRNA Stability
MRNA Transport
Regulation Of RNA Metabolic Process
CRD-mediated MRNA Stabilization
Neuronal Stem Cell Population Maintenance
Regulation Of Smooth Muscle Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Ectodermal Cell Differentiation
Positive Regulation Of Fibroblast Migration
Negative Regulation Of Angiogenesis
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Negative Regulation Of Interleukin-16 Production
Positive Regulation Of Interleukin-10 Production
Regulation Of Collagen Biosynthetic Process
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Vascular Associated Smooth Muscle Cell Differentiation
Myofibroblast Differentiation
Angiotensin-activated Signaling Pathway
Positive Regulation Of Macrophage Activation
Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching
Positive Regulation Of Macrophage Differentiation
Mesodermal Cell Differentiation
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Negative Regulation Of Protein Kinase B Signaling
Aorta Smooth Muscle Tissue Morphogenesis
Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Phenotypic Switching
Negative Regulation Of Somatic Stem Cell Population Maintenance
Negative Regulation Of Somatic Stem Cell Division
Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Pathways
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Alcohol consumption (
31358974
)
Alcohol use disorder (consumption score) (
30940813
)
Body fat percentage (
26833246
)
Brain morphology (MOSTest) (
32665545
)
Intelligence (MTAG) (
29326435
)
Primary tooth development (number of teeth) (
23704328
20195514
)
Primary tooth development (time to first tooth eruption) (
23704328
20195514
)
Prostate cancer (
23535732
)
Waist circumference (
31928498
)
Interacting Genes
76 interacting genes:
BIRC2
CDC42
CTNNB1
DUX4
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
79 interacting genes:
ADARB1
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP6
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
NONO
NUDT16L1
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
PUM1
RARS1
RBM14
RBM4
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYNCRIP
TAF15
TENT2
TIAL1
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
Entrez ID
10642
406937
HPRD ID
09752
Ensembl ID
ENSG00000159217
ENSG00000276365
Uniprot IDs
Q9NZI8
PDB IDs
3KRM
6QEY
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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