PRAF2 and HSD17B11

Data Source:
BioGRID (two hybrid)

		PRAF2	HSD17B11
Description		PRA1 domain family member 2	hydroxysteroid 17-beta dehydrogenase 11
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Membrane Membrane Integral Component Of Membrane	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Protein Binding	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Protein Transport L-glutamate Transmembrane Transport	Estrogen Biosynthetic Process Androgen Catabolic Process
Pathways			Estrogen biosynthesis
Drugs			Aetiocholanolone
Diseases
GWAS			Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)
Interacting Genes		26 interacting genes: ABHD16A ADGRD1 AGR3 AQP6 ARL6IP5 CCR5 CD79A CIAO2A CLEC10A EBAG9 GJA5 GJA8 GPR152 HIBADH HSD17B11 MCEMP1 MIEF1 NDRG4 REEP4 RETREG3 RNF5 SLC10A6 TLCD4 TMEM14B TMX2 ZDHHC15	59 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LNPEP LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SEC22B SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX5 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VAPA VEZT YIF1A YIPF6
Entrez ID		11230	51170
HPRD ID		06596	10881
Ensembl ID		ENSG00000243279	ENSG00000198189
Uniprot IDs		A0A024QZ22 O60831	Q8NBQ5
PDB IDs			1YB1
Enriched GO Terms of Interacting Partners?
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