SUMO4 and GMPS

Data Source:
HPRD (in vivo)

		SUMO4	GMPS
Description		small ubiquitin like modifier 4	guanine monophosphate synthase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus SUMO Ligase Complex	Cytosol
	Molecular Function	Molecular_function Protein Tag Ubiquitin-like Protein Ligase Binding	GMP Synthase Activity GMP Synthase (glutamine-hydrolyzing) Activity ATP Binding Pyrophosphatase Activity
	Biological Process	Protein Sumoylation Cellular Response To Oxidative Stress Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA Binding Negative Regulation Of DNA Binding Negative Regulation Of Transcription, DNA-templated Regulation Of Protein Localization To Nucleus	GMP Biosynthetic Process Glutamine Metabolic Process Purine Nucleobase Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process
Pathways			Purine ribonucleoside monophosphate biosynthesis
Drugs			Glutamic acid
Diseases
GWAS		Dupuytren's disease ( 28886342)	Blood metabolite levels ( 27453504) Cardiorespiratory fitness (800m run time) ( 32572135)
Interacting Genes		75 interacting genes: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5F1B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RACK1 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1	2 interacting genes: AGPAT2 SUMO4
Entrez ID		387082	8833
HPRD ID		10584	10927
Ensembl ID		ENSG00000177688	ENSG00000163655
Uniprot IDs		Q6EEV6	A0A140VJK6 P49915
PDB IDs			2VPI 2VXO
Enriched GO Terms of Interacting Partners?
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