TACC3 and TTF2

Data Source:
HPRD (two hybrid)

		TACC3	TTF2
Description		transforming acidic coiled-coil containing protein 3	transcription termination factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Cytosol Centriolar Satellite Intracellular Membrane-bounded Organelle Mitotic Spindle	Spliceosomal Complex Cytosol Transcription Elongation Factor Complex
	Molecular Function	Protein Binding	DNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity Zinc Ion Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Cell Population Proliferation Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis	DNA-templated Transcription, Termination Termination Of RNA Polymerase II Transcription MRNA Processing RNA Splicing
Pathways		NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Bladder cancer ( 24163127 20972438) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)
Interacting Genes		29 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 C2CD6 CCHCR1 CDC20B CIB3 CLIP4 EIF3C GDF15 IQCD KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C	25 interacting genes: CDC5L CDKL3 CLPB DCP1A DRAP1 GMEB2 HINFP HNRNPA1 HNRNPA2B1 KIF4A LINC01554 MATR3 MYB MYBL2 NVL PDCD6IP PRDX4 SKIL SMAD1 SMAD7 TACC3 TCF4 TNIP1 UBC ZSCAN1
Entrez ID		10460	8458
HPRD ID		05601	05280
Ensembl ID		ENSG00000013810	ENSG00000116830
Uniprot IDs		Q9Y6A5	Q9UNY4
PDB IDs		5LXN 5LXO 5ODS 5ODT
Enriched GO Terms of Interacting Partners?
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