TACC3 and CDC20B

Data Source:
BioGRID (two hybrid)

		TACC3	CDC20B
Description		transforming acidic coiled-coil containing protein 3	cell division cycle 20B
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Cytosol Centriolar Satellite Intracellular Membrane-bounded Organelle Mitotic Spindle	Anaphase-promoting Complex
	Molecular Function	Protein Binding	Protein Binding Anaphase-promoting Complex Binding Ubiquitin Ligase Activator Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Cell Population Proliferation Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis	Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Pathways		NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Bladder cancer ( 24163127 20972438) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)	Cocaine dependence ( 31212010)
Interacting Genes		29 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 C2CD6 CCHCR1 CDC20B CIB3 CLIP4 EIF3C GDF15 IQCD KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C	21 interacting genes: CCDC57 FHL5 GEMIN4 GOLGA2 KANK2 KRT31 KRT34 KRT40 MAGEA11 MDFI MTUS2 NUTM1 PLEKHF2 PLK2 SPAG5 TACC3 TRAF2 TRIM23 TRIM27 TRIM37 VPS52
Entrez ID		10460	166979
HPRD ID		05601	13428
Ensembl ID		ENSG00000013810	ENSG00000164287
Uniprot IDs		Q9Y6A5	Q86Y33
PDB IDs		5LXN 5LXO 5ODS 5ODT
Enriched GO Terms of Interacting Partners?
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