TACC3 and SPATA18

Data Source:
BioGRID (two hybrid)

		TACC3	SPATA18
Description		transforming acidic coiled-coil containing protein 3	spermatogenesis associated 18
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Cytosol Centriolar Satellite Intracellular Membrane-bounded Organelle Mitotic Spindle	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Cell Population Proliferation Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis	Cellular Response To DNA Damage Stimulus Mitochondrial Protein Catabolic Process Mitophagy By Induced Vacuole Formation
Pathways		NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Bladder cancer ( 24163127 20972438) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)	Height ( 31562340) Hip circumference adjusted for BMI ( 28552196) Platelet count ( 29403010) Type 2 diabetes ( 30054458) Uterine fibroids ( 30194396)
Interacting Genes		29 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 C2CD6 CCHCR1 CDC20B CIB3 CLIP4 EIF3C GDF15 IQCD KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C	13 interacting genes: AIMP2 CARD10 CCDC102B EFHC2 GAS8 GOLGA2 HOXA1 LRIF1 MAD1L1 PAXIP1 PIBF1 TACC3 TGM7
Entrez ID		10460	132671
HPRD ID		05601	14050
Ensembl ID		ENSG00000013810	ENSG00000163071
Uniprot IDs		Q9Y6A5	A0A140VKF4 Q8TC71
PDB IDs		5LXN 5LXO 5ODS 5ODT
Enriched GO Terms of Interacting Partners?
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