TACC3 and CLIP4

Data Source:
BioGRID (two hybrid)

		TACC3	CLIP4
Description		transforming acidic coiled-coil containing protein 3	CAP-Gly domain containing linker protein family member 4
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GO Annotations	Cellular Component	Spindle Pole Cytoplasm Cytosol Centriolar Satellite Intracellular Membrane-bounded Organelle Mitotic Spindle	Nucleus Cytoplasm Microtubule Plus-end Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding Microtubule Plus-end Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Cell Population Proliferation Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis	Cytoplasmic Microtubule Organization
Pathways		NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Bladder cancer ( 24163127 20972438) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)	Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 C2CD6 CCHCR1 CDC20B CIB3 CLIP4 EIF3C GDF15 IQCD KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C	33 interacting genes: APP CDK5RAP2 CLIP1 CMYA5 DCAF6 DES DST GLP1R HSF2BP JAKMIP2 KIF1B KIFC3 LZTS2 MAGEA12 MAP7 MAP7D1 MEOX2 MYBPC1 MYH3 PDE4DIP PEG10 SIX2 SON TACC3 TAF1 TNNT1 TNNT3 TPM1 TRIM32 TRIP13 TTN TULP3 ZNF114
Entrez ID		10460	79745
HPRD ID		05601	08634
Ensembl ID		ENSG00000013810	ENSG00000115295
Uniprot IDs		Q9Y6A5	A8K6D0 B7Z936 Q8N3C7
PDB IDs		5LXN 5LXO 5ODS 5ODT	2Z0W
Enriched GO Terms of Interacting Partners?
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