TTF2 and DRAP1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TTF2	DRAP1
Description		transcription termination factor 2	DR1 associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Spliceosomal Complex Cytosol Transcription Elongation Factor Complex	Nucleus Negative Cofactor 2 Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity Zinc Ion Binding	Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription, Termination Termination Of RNA Polymerase II Transcription MRNA Processing RNA Splicing	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil percentage of granulocytes ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		25 interacting genes: CDC5L CDKL3 CLPB DCP1A DRAP1 GMEB2 HINFP HNRNPA1 HNRNPA2B1 KIF4A LINC01554 MATR3 MYB MYBL2 NVL PDCD6IP PRDX4 SKIL SMAD1 SMAD7 TACC3 TCF4 TNIP1 UBC ZSCAN1	31 interacting genes: APP ARHGEF10L CDKN2C DNAJB11 DR1 FBXO7 FEZ1 FEZ2 FOXH1 GTF2B LMO2 LNX1 LNX2 MCRS1 MORF4L1 NCK2 NFYB PICK1 PIK3R3 PLEKHF2 POLE3 RPL9 SDCBP SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1
Entrez ID		8458	10589
HPRD ID		05280	03796
Ensembl ID		ENSG00000116830	ENSG00000175550
Uniprot IDs		Q9UNY4	Q14919
PDB IDs			1JFI
Enriched GO Terms of Interacting Partners?
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