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RBM14 and YWHAE
Data Source:
BioGRID
(two hybrid)
RBM14
YWHAE
Description
RNA binding motif protein 14
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Regulator Complex
Nucleolus
Cytoplasm
Nuclear Speck
Ribonucleoprotein Complex
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Kinesin Complex
Plasma Membrane
Focal Adhesion
Membrane
Melanosome
Extracellular Exosome
Central Region Of Growth Cone
Glutamatergic Synapse
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
Nuclear Receptor Coactivator Activity
RNA Binding
Calcium Channel Regulator Activity
Protein Binding
Potassium Channel Regulator Activity
Enzyme Binding
MHC Class II Protein Complex Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Histone Deacetylase Binding
Ion Channel Binding
Cadherin Binding
Protein Heterodimerization Activity
Phosphoserine Residue Binding
Phosphoprotein Binding
Scaffold Protein Binding
Biological Process
MRNA Splicing, Via Spliceosome
Activation Of Innate Immune Response
Response To Hormone
Histone Deacetylation
Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Centriole Replication
SMAD Protein Signal Transduction
Centriole Assembly
G2/M Transition Of Mitotic Cell Cycle
MAPK Cascade
Regulation Of Heart Rate By Hormone
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Viral Process
Substantia Nigra Development
Protein Localization To Nucleus
Cellular Response To Heat
Hippo Signaling
Intracellular Signal Transduction
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Protein Export From Nucleus
Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Membrane Repolarization
Membrane Organization
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Regulation Of Heart Rate By Cardiac Conduction
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Regulation Of Cellular Response To Heat
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Potassium Ion Transmembrane Transporter Activity
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Peptidyl-serine Dephosphorylation
Negative Regulation Of Calcium Ion Export Across Plasma Membrane
Pathways
RUNX2 regulates bone development
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Signaling by Hippo
NADE modulates death signalling
Regulation of PLK1 Activity at G2/M Transition
Regulation of HSF1-mediated heat shock response
HSF1 activation
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
AURKA Activation by TPX2
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
RAB GEFs exchange GTP for GDP on RABs
Drugs
Fusicoccin
Phenethyl Isothiocyanate
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Bipolar disorder (
21926972
)
Atrial fibrillation (
30061737
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Mean platelet volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Nicotine dependence symptom count (
25555482
)
Reaction time (
29844566
)
Schizophrenia (
28991256
30285260
)
Interacting Genes
113 interacting genes:
AKAP9
ATN1
CASK
CEP55
CRLF3
CTBP1
DDX17
DDX6
DMRTB1
DYNLT1
EP300
FMR1
FXR2
HNRNPK
HOMER3
KHDRBS2
KIFAP3
KLC4
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NCOA6
NDEL1
NFKBID
NR3C1
PARD6G
PARP1
PCBP1
PRKCI
QKI
RBM10
RBM5
RPA2
RUNX1
RUNX2
SLAIN1
SS18
SYT1
TARBP2
TRIM55
TRIM63
UBE2I
XRCC5
YWHAE
147 interacting genes:
-
ABL1
ACD
AKAP13
AKAP9
ANKHD1-EIF4EBP3
ANKZF1
ARHGEF2
ARHGEF28
ATP6V0B
ATXN1
BAD
BCR
BEX3
CALM1
CAP2
CASK
CASP3
CCDC125
CCR9
CDC25A
CDC25B
CDK11B
CDK14
CDK16
CDKN1B
CEP131
CEP95
CGNL1
CHAF1A
CHST11
CYSLTR2
DDX54
DISC1
DYRK1A
ENKD1
EXO1
FAM13B
FAM53C
FGF12
FHL1
FTH1
GAPDH
GPRIN2
GRAP2
GSTA1
GSTM3
GTF2B
HDAC4
HDAC5
HIVEP2
HNRNPC
HSF1
HSPB1
IGF1R
IL7R
ING1
IRAG2
IRS1
IRS2
ITPRID2
KANK1
KCNH2
KCNK15
KCNK3
KCNK9
KIAA0232
KIF1C
KLC4
KRT18
LCP2
MAGEB4
MAP3K1
MAP3K10
MAP3K2
MAP3K3
MAP3K5
MAPK7
MCM10
MDM4
METAP2
MSL2
MST1R
MT-CO2
MYH10
NAF1
NCOR2
NDEL1
NIN
PAPOLA
PARD3B
PCM1
PIMREG
PNLIP
POT1
PRC1
PRDX6
PRKCG
RAB11FIP2
RAF1
RAP1GAP2
RASAL3
RASGRF1
RBIS
RBM14
REM1
RGS3
RIN1
RPA2
RPGR
RXFP3
SAMSN1
SH3BP4
SLC8A1
SLC8A2
SLC8A3
SMAGP
SNAPIN
SNCA
SNF8
SORBS2
SRC
SYN2
TAF7
TAZ
TBC1D3F
TBP
TCEANC
TFDP2
TGFB1
TLK1
TNFAIP3
TOP2A
TSC1
TSC2
UBE3A
USP43
VIM
WNK1
WWTR1
YWHAB
YWHAG
YWHAH
YWHAQ
YWHAZ
ZC3HC1
ZNF839
Entrez ID
10432
7531
HPRD ID
11485
05457
Ensembl ID
ENSG00000239306
ENSG00000108953
Uniprot IDs
A0A0S2Z4Z0
A0A0S2Z567
A0A0S2Z5V2
Q96PK6
P62258
V9HW98
PDB IDs
2DNP
2BR9
3UAL
3UBW
6EIH
Enriched GO Terms of Interacting Partners
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