MAEA and RMND5A

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		MAEA	RMND5A
Description		macrophage erythroblast attacher, E3 ubiquitin ligase	required for meiotic nuclear division 5 homolog A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix GID Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm GID Complex
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Protein Ubiquitination Negative Regulation Of Myeloid Cell Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Erythrocyte Maturation Negative Regulation Of Gluconeogenesis Cell Division	Protein Polyubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs		Tetrachlorodecaoxide
Diseases
GWAS		Obesity-related traits ( 23251661) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969 26818947 23945395 32499647 22158537 30718926 28869590)	High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		12 interacting genes: ARMC8 GID4 GID8 MKLN1 MYOC RANBP10 RMND5A UBE2D2 UBE2D3 UBE2H UBE2R2 YPEL5	8 interacting genes: APP GID8 MAEA MEOX2 SMAD9 UBE2D1 UBE2D2 VKORC1
Entrez ID		10296	64795
HPRD ID		08427	07841
Ensembl ID		ENSG00000090316	ENSG00000153561
Uniprot IDs		B3KRN7 B4DJP8 B4DQT1 B4DVN3 D6RIB6 Q7L5Y9	Q9H871
PDB IDs
Enriched GO Terms of Interacting Partners?
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