MAEA and YPEL5

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MAEA	YPEL5
Description		macrophage erythroblast attacher, E3 ubiquitin ligase	yippee like 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix GID Complex	Ubiquitin Ligase Complex Extracellular Region Nucleus Centrosome Midbody Mitotic Spindle Pole Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Protein Ubiquitination Negative Regulation Of Myeloid Cell Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Erythrocyte Maturation Negative Regulation Of Gluconeogenesis Cell Division	Cell Population Proliferation Neutrophil Degranulation
Pathways			Neutrophil degranulation
Drugs		Tetrachlorodecaoxide
Diseases
GWAS		Obesity-related traits ( 23251661) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969 26818947 23945395 32499647 22158537 30718926 28869590)	Celiac disease and Rheumatoid arthritis ( 26546613) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		12 interacting genes: ARMC8 GID4 GID8 MKLN1 MYOC RANBP10 RMND5A UBE2D2 UBE2D3 UBE2H UBE2R2 YPEL5	13 interacting genes: CTDSP1 DDIT4L FBXO7 GSC2 MAEA MAPKBP1 PFDN5 PLAGL2 PSMA1 RANBP9 SHC3 TRAF5 ZNF655
Entrez ID		10296	51646
HPRD ID		08427	18312
Ensembl ID		ENSG00000090316	ENSG00000119801
Uniprot IDs		B3KRN7 B4DJP8 B4DQT1 B4DVN3 D6RIB6 Q7L5Y9	P62699
PDB IDs
Enriched GO Terms of Interacting Partners?
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