MAEA and ARMC8

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MAEA	ARMC8
Description		macrophage erythroblast attacher, E3 ubiquitin ligase	armadillo repeat containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix GID Complex	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol GID Complex Specific Granule Lumen Intracellular Membrane-bounded Organelle Tertiary Granule Lumen
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Metal Ion Binding	Protein Binding
	Biological Process	Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Protein Ubiquitination Negative Regulation Of Myeloid Cell Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Erythrocyte Maturation Negative Regulation Of Gluconeogenesis Cell Division	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Neutrophil Degranulation
Pathways			Neutrophil degranulation
Drugs		Tetrachlorodecaoxide
Diseases
GWAS		Obesity-related traits ( 23251661) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969 26818947 23945395 32499647 22158537 30718926 28869590)	Mean spheric corpuscular volume ( 32888494)
Interacting Genes		12 interacting genes: ARMC8 GID4 GID8 MKLN1 MYOC RANBP10 RMND5A UBE2D2 UBE2D3 UBE2H UBE2R2 YPEL5	8 interacting genes: CIB3 CTNNA1 GID8 MAEA STX6 TCF12 TNNT1 ZMYND12
Entrez ID		10296	25852
HPRD ID		08427	09992
Ensembl ID		ENSG00000090316	ENSG00000114098
Uniprot IDs		B3KRN7 B4DJP8 B4DQT1 B4DVN3 D6RIB6 Q7L5Y9	B7Z637 Q8IUR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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