MAEA and MKLN1

Data Source:
BioGRID (pull down)

		MAEA	MKLN1
Description		macrophage erythroblast attacher, E3 ubiquitin ligase	muskelin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix GID Complex	Ubiquitin Ligase Complex Ruffle Nucleoplasm Cytoplasm Cytosol Cell Cortex Postsynapse
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Metal Ion Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Protein Ubiquitination Negative Regulation Of Myeloid Cell Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Erythrocyte Maturation Negative Regulation Of Gluconeogenesis Cell Division	Regulation Of Receptor Internalization Cell-matrix Adhesion Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Reorganization
Pathways
Drugs		Tetrachlorodecaoxide
Diseases
GWAS		Obesity-related traits ( 23251661) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969 26818947 23945395 32499647 22158537 30718926 28869590)	Asthma (childhood onset) ( 23829686) Bipolar disorder ( 31043756) Bipolar disorder (early onset) ( 27769005) Cutaneous malignant melanoma ( 32341527) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Hyperglycemia in higher physical activity ( 30327367) Hypertension ( 28273873) Lung cancer in never smokers ( 28604730) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Myeloproliferative neoplasms ( 33057200) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Pancreatic cancer ( 25086665) PR interval ( 30046033 32439900) Refractive error ( 32231278) Resting heart rate ( 27798624) Staphylococcus aureus nasal carriage (persistent) ( 26569114) Systolic blood pressure ( 28135244) Vitamin D levels ( 25208829) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		12 interacting genes: ARMC8 GID4 GID8 MKLN1 MYOC RANBP10 RMND5A UBE2D2 UBE2D3 UBE2H UBE2R2 YPEL5	5 interacting genes: CYREN LAMTOR5 MAEA PTGER3 ZBTB2
Entrez ID		10296	4289
HPRD ID		08427	16129
Ensembl ID		ENSG00000090316	ENSG00000128585
Uniprot IDs		B3KRN7 B4DJP8 B4DQT1 B4DVN3 D6RIB6 Q7L5Y9	B4DG30 Q9UL63
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?