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SF3A1 and MIR145
Data Source:
BioGRID
(unspecified method)
SF3A1
MIR145
Description
splicing factor 3a subunit 1
microRNA 145
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
U2-type Spliceosomal Complex
U2 SnRNP
Nuclear Speck
U2-type Prespliceosome
U2-type Precatalytic Spliceosome
Catalytic Step 2 Spliceosome
Extracellular Exosome
Molecular Function
RNA Binding
Protein Binding
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA 3'-splice Site Recognition
MRNA Splicing, Via Spliceosome
MRNA Processing
U2-type Prespliceosome Assembly
Regulation Of Smooth Muscle Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Ectodermal Cell Differentiation
Positive Regulation Of Fibroblast Migration
Negative Regulation Of Angiogenesis
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Negative Regulation Of Interleukin-16 Production
Positive Regulation Of Interleukin-10 Production
Regulation Of Collagen Biosynthetic Process
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Vascular Associated Smooth Muscle Cell Differentiation
Myofibroblast Differentiation
Angiotensin-activated Signaling Pathway
Positive Regulation Of Macrophage Activation
Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching
Positive Regulation Of Macrophage Differentiation
Mesodermal Cell Differentiation
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Negative Regulation Of Protein Kinase B Signaling
Aorta Smooth Muscle Tissue Morphogenesis
Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Phenotypic Switching
Negative Regulation Of Somatic Stem Cell Population Maintenance
Negative Regulation Of Somatic Stem Cell Division
Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Pathways
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Delirium (
29631748
)
Eosinophil percentage of white cells (
32888494
)
Urinary albumin-to-creatinine ratio (
31511532
)
Interacting Genes
60 interacting genes:
APBB1
CSNK2A1
DDX42
GAS7
IL7R
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-2
MIR138-2
MIR141
MIR145
MIR155
MIR15A
MIR15B
MIR18A
MIR18B
MIR199A2
MIR19B1
MIR19B2
MIR200B
MIR200C
MIR20B
MIR214
MIR221
MIR25
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR363
MIR451A
MIR7-1
MIR7-3
MIR92A2
MIRLET7A1
MIRLET7A2
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F2
MIRLET7G
MIRLET7I
PRPF40A
RBFOX2
RBM10
SF1
SF3A2
SF3A3
SMAD3
SMURF1
SP1
SUMO2
TCERG1
WBP4
WDR77
79 interacting genes:
ADARB1
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP6
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
NONO
NUDT16L1
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
PUM1
RARS1
RBM14
RBM4
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYNCRIP
TAF15
TENT2
TIAL1
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
Entrez ID
10291
406937
HPRD ID
06903
Ensembl ID
ENSG00000099995
ENSG00000276365
Uniprot IDs
A0A024R1K8
Q15459
PDB IDs
1ZKH
2DT6
2DT7
5Z56
5Z57
5Z58
6AH0
6AHD
6FF7
6QX9
6Y53
6Y5Q
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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