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TNK2 and ITFG2
Data Source:
HPRD
(two hybrid)
TNK2
ITFG2
Description
tyrosine kinase non receptor 2
integrin alpha FG-GAP repeat containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endosome
Cytosol
Plasma Membrane
Clathrin-coated Pit
Adherens Junction
Membrane
Clathrin-coated Vesicle
Cytoplasmic Vesicle Membrane
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Perinuclear Region Of Cytoplasm
Grb2-EGFR Complex
Cytoophidium
Nucleoplasm
Lysosomal Membrane
Cytosol
KICSTOR Complex
Molecular Function
Protein Serine/threonine/tyrosine Kinase Activity
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
GTPase Inhibitor Activity
Signaling Receptor Binding
Epidermal Growth Factor Receptor Binding
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Metal Ion Binding
WW Domain Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Endocytosis
Cell Surface Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Small GTPase Mediated Signal Transduction
Phosphorylation
Cell Differentiation
Negative Regulation Of GTPase Activity
Innate Immune Response
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Clathrin-dependent Endocytosis
Germinal Center B Cell Differentiation
Regulation Of TOR Signaling
Cellular Response To Amino Acid Starvation
Cellular Response To Glucose Starvation
Negative Regulation Of TORC1 Signaling
Pathways
Amino acids regulate mTORC1
Drugs
ATP
Debromohymenialdisine
Entrectinib
Fostamatinib
Diseases
GWAS
Asthma (
31959851
)
Bronchopulmonary dysplasia (
23897914
)
Low density lipoprotein cholesterol levels (
30498476
)
Total cholesterol levels (
30498476
)
Interacting Genes
49 interacting genes:
AKT1
AQP1
AR
ARSL
BAG3
CDC42
CLTC
CSPG4
CTTN
CYSRT1
DPH2
EGFR
FGFR1
FYN
GALT
GRB2
HCK
HECW1
HSH2D
HSP90AB2P
ITFG2
KCNA5
KRTAP10-3
MAGI3
MCF2
MERTK
NCK1
NEK6
NOTCH2NLA
NPHP1
PDGFRB
PIK3R3
RASGEF1C
RASGRF1
RPL18A
SEZ6
SH2D1A
SH2D1B
SIAH1
SMURF1
SNX9
SOCS4
SRC
SRSF5
VTI1B
WAS
WWOX
WWP2
YES1
1 interacting genes:
TNK2
Entrez ID
10188
55846
HPRD ID
06104
14379
Ensembl ID
ENSG00000061938
ENSG00000111203
Uniprot IDs
A0A499FJ16
A0A5F9ZGX5
A0A5F9ZHJ2
B3KXJ4
C9J1X3
Q07912
A0A0S2Z5G6
A0A0S2Z5P1
Q969R8
PDB IDs
1CF4
1U46
1U4D
1U54
3EQP
3EQR
4EWH
4HZR
4HZS
4ID7
5ZXB
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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