FOSB and CYTH4

Data Source:
BioGRID (two hybrid)

		FOSB	CYTH4
Description		FosB proto-oncogene, AP-1 transcription factor subunit	cytohesin 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Golgi Membrane Cytosol Plasma Membrane Centriolar Satellite Intercellular Bridge
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Female Pregnancy Response To Mechanical Stimulus Response To Progesterone Cellular Response To Hormone Stimulus Response To Drug Response To Morphine Positive Regulation Of Transcription By RNA Polymerase II Response To Corticosterone Response To CAMP Cellular Response To Calcium Ion	Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		Estrogen-dependent gene expression NGF-stimulated transcription NGF-stimulated transcription	Intra-Golgi traffic
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Heel bone mineral density ( 30598549 28869591)	Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Uterine fibroids ( 28836065)
Interacting Genes		28 interacting genes: AGXT ATF2 CENPO CREB5 CYTH4 DNMT3L ENKD1 EP300 FAM222B FAM90A1 FOXP3 GLIS2 JUN JUNB JUND NCK2 NEDD9 PHC2 PHF1 POGZ POU6F2 ROR2 SRA1 TENT5B TLE5 TLX3 VEZF1 ZC3H10	24 interacting genes: AMOTL2 CBY2 CCDC120 CCDC197 CCDC6 CNKSR1 CTAG1A CTAG1B FOS FOSB HOOK2 IPCEF1 KANK2 KIFC3 KRT15 KRT16 KRT34 KRT40 PCM1 PSMB1 SNAPC5 SYCE1L TRIM54 USHBP1
Entrez ID		2354	27128
HPRD ID		01270	07354
Ensembl ID		ENSG00000125740	ENSG00000100055
Uniprot IDs		A0A024R0P6 K7EKC1 P53539	B4E2V8 Q9UIA0
PDB IDs		5VPA 5VPB 5VPC 5VPD 5VPE 5VPF 6UCI 6UCL 6UCM
Enriched GO Terms of Interacting Partners?
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