GGCX

Description		gamma-glutamyl carboxylase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Gamma-glutamyl Carboxylase Activity Vitamin Binding
	Biological Process	Cellular Protein Modification Process Blood Coagulation Peptidyl-glutamic Acid Carboxylation
Pathways		Gamma-carboxylation of protein precursors Gamma-carboxylation of protein precursors Defective gamma-carboxylation of F9
Drugs		Coagulation factor VIIa Recombinant Human Coagulation Factor IX (Recombinant) Glutamic acid Menadione Phylloquinone Anisindione Kappadione Coagulation Factor IX Human
Diseases		Pseudoxanthoma elasticum, including: Pseudoxanthoma elasticum (PXE); Pseudoxanthoma elasticum-like disorder with multiple coagulation factor deficiency Combined deficiency of vitamin K-dependent clotting factors (VKCFD)
GWAS		Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) High light scatter reticulocyte count ( 32888494) Myocardial infarction ( 26343387) Prostate cancer ( 21743467) Triglyceride levels ( 32203549)
Novel Interacting Genes		7 novel interacting genes: ARFGAP1 ATP2C1 CD8A FXN PDCD5 PPM1G ST3GAL4
Interacting Genes		7 interacting genes: BGLAP F10 F2 F7 F9 PROC SRPK2
Entrez ID		2677
HPRD ID		00665
Ensembl ID		ENSG00000115486
Uniprot IDs		P38435
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?