TECR and PGRMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TECR	PGRMC2
Description		trans-2,3-enoyl-CoA reductase	progesterone receptor membrane component 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Oxidoreductase Activity Very-long-chain-acyl-CoA Dehydrogenase Activity Very-long-chain Enoyl-CoA Reductase Activity	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding
	Biological Process	Sphingolipid Metabolic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development
Pathways		Synthesis of very long-chain fatty acyl-CoAs	RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS			Bone mineral density (total hip) ( 29883787)
Interacting Genes		28 interacting genes: ARL13B CD79A CLDN5 CRB3 CREB3 CREB3L1 ELOVL4 ERGIC3 FAM209A FBXO7 GET1 GOLT1A HACD1 JAGN1 MFSD14B MMGT1 MUC1 NOS3 PAXIP1 PGRMC2 PTEN RETREG3 SLC10A6 SLC7A14 STING1 STOM TFAM VMA21	57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1
Entrez ID		9524	10424
HPRD ID		17076	09665
Ensembl ID		ENSG00000099797	ENSG00000164040
Uniprot IDs		B3KSQ1 Q9NZ01	O15173
PDB IDs		2DZJ
Enriched GO Terms of Interacting Partners?
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