PGRMC2 and TMEM107

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PGRMC2	TMEM107
Description		progesterone receptor membrane component 2	transmembrane protein 107
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Integral Component Of Membrane Ciliary Transition Zone MKS Complex
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Molecular_function Protein Binding
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Detection Of Nodal Flow Regulation Of Gene Expression Neural Tube Patterning Embryonic Digit Morphogenesis Roof Of Mouth Development Cilium Assembly Craniofacial Suture Morphogenesis Protein Localization To Ciliary Transition Zone Non-motile Cilium Assembly
Pathways		RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787)	Diastolic blood pressure ( 30224653) Urinary potassium excretion ( 31409800)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	44 interacting genes: AQP3 AQP6 BIK CCL21 CD40 CD79A CLN8 CLSTN3 EBAG9 ERGIC3 EVI2B FAM209A FAM210B FCER1G GJA5 GJA8 GPX8 KCNA5 KCNJ6 LHFPL5 LMNA MGST3 MS4A3 PDZK1IP1 PGRMC2 PIGP SAR1A SLC10A6 SLC30A2 SLC35C2 SLC39A2 SYT2 THAP4 TMEM106A TMEM139 TMEM167B TMEM234 TMEM237 TMEM31 TMEM51 TMEM52B TMEM80 TMEM86B VMA21
Entrez ID		10424	84314
HPRD ID		09665	14400
Ensembl ID		ENSG00000164040	ENSG00000179029
Uniprot IDs		O15173	Q6UX40
PDB IDs
Enriched GO Terms of Interacting Partners?
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