PGRMC2 and SLC38A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PGRMC2	SLC38A1
Description		progesterone receptor membrane component 2	solute carrier family 38 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Axon Neuronal Cell Body Extracellular Exosome External Side Of Apical Plasma Membrane
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Amino Acid:sodium Symporter Activity Neutral Amino Acid:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Neurotransmitter Uptake Amino Acid Transmembrane Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Female Pregnancy Neutral Amino Acid Transport L-amino Acid Transport Transport Across Blood-brain Barrier L-alpha-amino Acid Transmembrane Transport
Pathways		RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle	Astrocytic Glutamate-Glutamine Uptake And Metabolism Amino acid transport across the plasma membrane
Drugs			Asparagine
Diseases
GWAS		Bone mineral density (total hip) ( 29883787)	Birth weight ( 31043758) Gout ( 32238385) Morning person ( 30696823) Offspring birth weight ( 31043758) Refractive error ( 32231278)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	30 interacting genes: AMIGO1 AQP6 BMP10 C1QL4 CD79A CREB3 FATE1 FFAR2 GPR152 GPR42 GRM2 IGFBP5 IL1RL1 PDCD1LG2 PGRMC2 PMP22 PTPN11 RPRM SCGB1D1 SCN3B SERP2 SLC10A1 SLC10A6 SLC13A4 SMIM3 SSMEM1 STRIT1 TMEM60 TMPPE TRARG1
Entrez ID		10424	81539
HPRD ID		09665	12245
Ensembl ID		ENSG00000164040	ENSG00000111371
Uniprot IDs		O15173	A0A024R124 F8VX04 Q9H2H9
PDB IDs
Enriched GO Terms of Interacting Partners?
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