PGRMC2 and UBXN8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PGRMC2	UBXN8
Description		progesterone receptor membrane component 2	UBX domain protein 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Ubiquitin Ligase Complex Nucleoplasm Nucleolus Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Single Fertilization Ubiquitin-dependent ERAD Pathway
Pathways		RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	13 interacting genes: ADRB3 AQP6 C8orf86 DCTN6 GJA8 HSD17B13 MEOX2 PGRMC2 RBPMS SFRP1 SPCS1 TMEM14B WRN
Entrez ID		10424	7993
HPRD ID		09665	03692
Ensembl ID		ENSG00000164040	ENSG00000104691
Uniprot IDs		O15173	B4DKK1 O00124
PDB IDs
Enriched GO Terms of Interacting Partners?
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