PGRMC2 and AQP10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PGRMC2	AQP10
Description		progesterone receptor membrane component 2	aquaporin 10
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Lipid Droplet Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Water Transport Response To Toxic Substance Glycerol Transport Protein Homotetramerization Cellular Response To Acidic PH Urea Transmembrane Transport
Pathways		RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle	Passive transport by Aquaporins
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787)	Bipolar disorder ( 31043756) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Non-albumin protein levels ( 29403010) Parkinson's disease progression (motor) ( 33111402) Red cell distribution width ( 32888494) Serum total protein level ( 29403010)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	20 interacting genes: ARL13B CISD2 CREB3L1 CYBC1 ERGIC3 GPR152 GPR37L1 KIR2DL3 LMNA LYVE1 MGST3 NEMP1 PGRMC2 PLP1 PVR SAR1A SCN3B SSMEM1 SYT2 TMEM167B
Entrez ID		10424	89872
HPRD ID		09665	07361
Ensembl ID		ENSG00000164040	ENSG00000143595
Uniprot IDs		O15173	Q96PS8
PDB IDs			6F7H
Enriched GO Terms of Interacting Partners?
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