PGRMC2 and EI24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PGRMC2	EI24
Description		progesterone receptor membrane component 2	EI24 autophagy associated transmembrane protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Protein Binding Importin-alpha Family Protein Binding
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Apoptotic Process Macroautophagy Negative Regulation Of Cell Growth
Pathways		RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787)	Alanine aminotransferase levels ( 33547301) Body mass index ( 28552196)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	8 interacting genes: BNIP2 CCR8 KCNJ1 NRGN PGRMC2 RABAC1 TMED8 TMEM14B
Entrez ID		10424	9538
HPRD ID		09665	05526
Ensembl ID		ENSG00000164040	ENSG00000149547
Uniprot IDs		O15173	A0A024R3I8 E9PK61 O14681
PDB IDs
Enriched GO Terms of Interacting Partners?
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